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Article

Genomic determinants of biological aggressiveness and poor prognosis of pancreatic cancers: KRAS and beyond.

Expert review of molecular diagnostics - 1 May 2024

Ciulla Calogero, Luchini Claudio

Abstract excerpt

INTRODUCTION: A marked histomolecular heterogeneity characterizes pancreatic cancer. Thus, different tumor histologies with divergent genomic profiles exist within the same category. AREAS COVERED: Using data from PubMed, SCOPUS, and Embase (last search date: 04/04/2024), this expert-based, narrative review presents and discusses the essential molecular determinants of biological aggressiveness and poor prognosis...

Topics

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Biomarkers, Tumor
SMAD4 gene
TP53 gene
Genomics
Mutation
Pancreatic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins p21(ras)

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Identifiers

PMID: 38708441
DOI: 10.1080/14737159.2024.2348676

Genes

KRAS
SMAD4
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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