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Genomic alterations in pancreatic cystic neoplasms: from molecular characterization to precision clinical management

27 Jun 2025

Abstract excerpt

Pancreatic cystic neoplasms (PCNs) are a heterogeneous group of pancreatic lesions with the potential for malignant transformation. Next-generation sequencing has revealed subtype-specific driver mutations and pathways that govern the initiation and progression of PCN. Evidence suggests that subtype-specific genetic trajectories and temporal sequences of genetic and molecular events are pivotal in determining...

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PMID: 40576137
DOI: 10.1097/js9.0000000000002814

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