Article
Pinpoint the Positions of Single Nucleotide Polymorphisms by a Nanocluster Dimer.
Analytical chemistry - 21 Feb 2017
Liu Jie, Lu Yuexiang, Feng Lu, Wang Song, Zhang Shixi, Zhu Xuewei, Sheng Linfeng, Zhang Sichun, Zhang Xinrong
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most fundamental internal causes for many genetic diseases. However, the location information on SNPs in a specific DNA sequence is not well acquired through current SNPs detection methods, except for accurate DNA sequencing. Here we report a fluorescence enhancement phenomenon in the process of two silver nanoclusters (AgNCs) approaching closely to form a...
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