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Gap site-specific rapid formation of fluorescent silver nanoclusters for label-free DNA nucleobase recognition.

Analytica chimica acta - 29 Apr 2012

Cui Qinghua, Ma Kun, Shao Yong, Xu Shujuan, Wu Fei, Liu Guiying, Teramae Norio, Bao Haifeng

Abstract excerpt

Silver nanoclusters (Ag NCs) templated with DNAs have attracted much attention as novel fluorophores because of their convenient emission tunability by the sequence and length of the template DNAs. However, the precise production of Ag NCs in a site-specific manner still remains a challenge to attain highly selective and label-free DNA recognition. Here we exploited the availability of a gap site in DNA duplexes...

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PMID: 22483214
DOI: 10.1016/j.aca.2012.02.044

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