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DNA Three-Way Junction for Differentiation of Single-Nucleotide Polymorphisms with Fluorescent Copper Nanoparticles.

Chemistry (Weinheim an der Bergstrasse, Germany) - 23 May 2017

Sun Feifei, You Ying, Liu Jie, Song Quanwei, Shen Xiaotong, Na Na, Ouyang Jin

Abstract excerpt

A label- and enzyme-free fluorescent sensor for the detection of single-nucleotide polymorphisms (SNPs) at room temperature is proposed, using new copper nanoparticles (CuNPs) as fluorescent reporters. The CuNPs were constructed by using a DNA three-way junction (3WJ) template. In this assay, two complementary adenine/thymine-rich probes can hybridize with the wild-type target simultaneously to construct a 3WJ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28370648
DOI: 10.1002/chem.201701361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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