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Article

MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging

13 Feb 2017

Abstract excerpt

BACKGROUND: A widespread modulation of gene expression occurs in the aging brain, but little is known as to the upstream drivers of these changes. MicroRNAs emerged as fine regulators of gene expression in many biological contexts and they are modulated by age. MicroRNAs may therefore be part of the upstream drivers of the global gene expression modulation correlated with aging and aging-related phenotypes....

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PMID: 28193224
DOI: 10.1186/s12915-017-0354-x

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