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Article

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors

26 Oct 2021

Abstract excerpt

BACKGROUND: Skeletal muscle atrophy is a debilitating complication of many chronic diseases, disuse conditions, and ageing. Genome-wide gene expression analyses have identified that elevated levels of microRNAs encoded by the H19X locus are among the most significant changes in skeletal muscles in a wide scope of human cachectic conditions. We have previously reported that the H19X locus is important for the...

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PMID: 34704401
DOI: 10.1002/jcsm.12827

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