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Article

The SLC6A3 gene possibly affects susceptibility to late-onset alcohol dependence but not specific personality traits in a Han Chinese population.

PloS one - 1 Jan 2017

Huang Chang-Chih, Kuo Shin-Chang, Yeh Yi-Wei, Chen Chun-Yen, Yen Che-Hung, Liang Chih-Sung, Ho Pei-Shen, Lu Ru-Band, Huang San-Yuan

Abstract excerpt

Dopaminergic dysfunction has an important role in the pathoetiology of alcohol dependence (AD). The purpose of this study was to determine whether the solute carrier family 6 member 3 (SLC6A3) gene (also known as the dopamine transporter DAT gene) was associated with AD, and whether variants in the SLC6A3 locus were associated with specific personality traits in patients with AD. Sixteen polymorphisms in SLC6A3...

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Identifiers

PMID: 28182634
DOI: 10.1371/journal.pone.0171170
PMCID: PMC5300170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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