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Article

Novelty seeking mediates the effect of DRD3 variation on onset age of amphetamine dependence in Han Chinese population.

European archives of psychiatry and clinical neuroscience - 1 Apr 2018

Kuo Shin-Chang, Yeh Yi-Wei, Chen Chun-Yen, Huang Chang-Chih, Chen Tien-Yu, Yen Che-Hung, Liang Chih-Sung, Ho Pei-Shen, Lu Ru-Band, Huang San-Yuan

Abstract excerpt

The dopamine receptor D3 (DRD3) gene, one of the candidate genes for amphetamine dependence (AD), is involved in the mesolimbic dopaminergic system, implicated as the underlying mechanism of addiction. Our case-control study aimed to investigate whether the DRD3 gene is associated with the susceptibility to AD and specific personality traits in AD patients. A total of 1060 unrelated Han Chinese subjects (559 AD...

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Source

Identifiers

PMID: 28028606
DOI: 10.1007/s00406-016-0754-x

Genes

DRD3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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