Article
Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence.
Journal of molecular neuroscience : MN - 1 Feb 2012
Wang Ke-Sheng, Liu Xuefeng, Aragam Nagesh, Mullersman Jerald E, Jian Xueqiu, Pan Yue, Liu Yali
Abstract excerpt
Personality traits like novelty seeking (NS), harm avoidance (HA), and reward dependence (RD) are known to be moderately heritable (30-60%). These personality traits and their comorbidities, such as alcohol dependence (AD), may share genetic components. We examined 11,120 single nucleotide polymorphisms (SNPs) genotyped in 292 nuclear families from the Genetic Analysis Workshop 14, a subset from the Collaborative...
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