Article
The dopamine transporter gene may not contribute to susceptibility and the specific personality traits of amphetamine dependence.
Drug and alcohol dependence - 1 Apr 2015
Tzeng Nian-Sheng, Lu Ru-Band, Yeh Hui-Wen, Yeh Yi-Wei, Huang Chang-Chih, Yen Che-Hung, Kuo Shin-Chang, Chen Chun-Yen, Chang Hsin-An, Ho Pei-Shen, Cheng Serena, Shih Mei-Chen, Huang San-Yuan
Abstract excerpt
BACKGROUND: A substantial amount of evidence suggests that dysfunction of the dopamine transporter may be involved in the pathophysiology of amphetamine dependence (AD). The aim of this study was to examine whether the dopamine transporter gene (DAT1, SLC6A3) is associated with development of AD and whether this gene influences personality traits in patients with AD. METHODS: Eighteen polymorphisms of the DAT1...
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