Article
Genetic association of SLC6A3 (dopamine transporter) gene polymorphisms with personality disorders and substance abuse disorders: a systematic review and meta-analysis.
Psychiatric genetics - 1 Oct 2024
Vogiatzoglou Angeliki V, Kontou Panagiota I, Bagos Pantelis G, Braliou Georgia G
Abstract excerpt
INTRODUCTION: Personality disorders (PD) are characterized by socially dysfunctional behavioral patterns that affect patients and show higher incidence rates within families. Substance abuse disorders (SAD) are exemplified by extensive and prolonged use of substances, including alcohol, nicotine, or illegal drugs. Genetic predisposition for both PD and SAD has been reported to involve gene variants regulating...
Topics
- Humans
- Dopamine Plasma Membrane Transport Proteins
- Genetic Association Studies
- Genetic Predisposition to Disease
- Personality Disorders
- Polymorphism, Single Nucleotide
- Substance-Related Disorders