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The role of personality traits and life stress in alcohol use disorder: Insights from NGF gene polymorphisms of Han Chinese population in Taiwan.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

Kuo Shin-Chang, Lin Chun-Long, Yeh Yi-Wei, Chen Chun-Yen, Huang Yu-Chieh, Chang Ting-Yu, Yang You-Ping, Huang Jhih-Syuan, Yang Bao-Zhu, Huang San-Yuan

Abstract excerpt

OBJECTIVE: Alcohol use disorder (AUD) is a complex neuropsychiatric condition influenced by genetic and environmental factors. Nerve growth factor (NGF) plays a crucial role in neuronal neuroplasticity and chronic alcohol consumption may alter NGF levels in specific brain regions. The study investigates the associations between NGF gene polymorphisms, susceptibility to AUD, and specific stress and personality...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 39719220
DOI: 10.1016/j.pnpbp.2024.111232
PMCID: PMC12010415

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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