DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans.

doi:10.1159/000358062

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans.

Neuropsychobiology - 1 Jan 2014

Kang Seung-Gul, Lee Bun-Hee, Lee Jun-Seok, Chai Young Gyu, Ko Kwang-Pil, Lee Heon-Jeong, Han Dal Mu Ri, Ji Hong, Jang Gyeong-Ho, Shin Hye Eun

Abstract excerpt

BACKGROUND: Several polymorphisms of the dopamine D3 receptor (DRD3) gene are reported to be involved in the susceptibility to alcoholism. Although the DRD3 rs6280 (Ser9Gly) polymorphism plays an important role in various psychiatric disorders, findings regarding the association between this single-nucleotide polymorphism (SNP) and alcohol dependence (AD) have been inconsistent. Therefore, the present study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Case-Control Studies

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, Dopamine D3

Source

Open in PubMed

Identifiers

PMID: 24776816
DOI: 10.1159/000358062

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DRD3 gene rs6280 polymorphism may be associated with alcohol dependence overall and with Lesch type I alcohol dependence in Koreans.PMID 24776816Read ↗

The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology.Semantic proximity Read ↗

No association between the dopamine D3 receptor gene and Korean alcohol dependence.Semantic proximity Read ↗

Association study of the SLC6A3 VNTR (DAT) and DRD2/ANKK1 Taq1A polymorphisms with alcohol dependence in a population from northeastern Brazil.Semantic proximity Read ↗

Limited associations of dopamine system genes with alcohol dependence and related traits in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD).Semantic proximity Read ↗

Association of alcohol dehydrogenase 1C gene *1/*2 polymorphism with alcohol Dependence(AD) in Turkey: A meta-analysis.Semantic proximity Read ↗

Association study of DKK2 polymorphisms with alcohol dependence and alcohol-related harm.Semantic proximity Read ↗

Case-control association analysis of dopamine receptor polymorphisms in alcohol dependence: a pilot study in Indian males.Semantic proximity Read ↗

Common variants in HLA-DRA gene are associated with alcohol dependence in two Caucasian samples.Semantic proximity Read ↗

Extended genetic effects of ADH cluster genes on the risk of alcohol dependence: from GWAS to replication.Semantic proximity Read ↗

PER3 polymorphism and insomnia severity in alcohol dependence.Semantic proximity Read ↗

Meta-Analysis Reveals Significant Association of the 3'-UTR VNTR in SLC6A3 with Alcohol Dependence.Semantic proximity Read ↗

DRD2/ANKK1 TaqIA and SLC6A3 VNTR polymorphisms in alcohol dependence: association and gene-gene interaction study in a population of Central Italy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.