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Article

Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.

The Journal of biological chemistry - 31 Mar 2017

Remesh Soumya G, Andreatta Massimo, Ying Ge, Kaever Thomas, Nielsen Morten, McMurtrey Curtis, Hildebrand William, Peters Bjoern, Zajonc Dirk M

Abstract excerpt

Peptide antigen presentation by major histocompatibility complex (MHC) class I proteins initiates CD8+ T cell-mediated immunity against pathogens and cancers. MHC I molecules typically bind peptides with 9 amino acids in length with both ends tucked inside the major A and F binding pockets. It has been known for a while that longer peptides can also bind by either bulging out of the groove in the middle of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28179428
DOI: 10.1074/jbc.M117.776542
PMCID: PMC5392673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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