Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock.

doi:10.1097/PCC.0000000000001058

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Article

Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 1 Apr 2017

Cvijanovich Natalie Z, Anas Nick, Allen Geoffrey L, Thomas Neal J, Bigham Michael T, Weiss Scott L, Fitzgerald Julie, Checchia Paul A, Meyer Keith, Quasney Michael, Gedeit Rainer, Freishtat Robert J, Nowak Jeffrey, Raj Shekhar S, Gertz Shira, Grunwell Jocelyn R, Opoka Amy, Wong Hector R

Abstract excerpt

OBJECTIVE: Polymorphisms of the glucocorticoid receptor gene are associated with outcome and corticosteroid responsiveness among patients with inflammatory disorders. We conducted a candidate gene association study to test the hypothesis that these polymorphisms are associated with outcome and corticosteroid responsiveness among children with septic shock. DESIGN: We genotyped 482 children with septic shock for...

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Identifiers

PMID: 28178077
DOI: 10.1097/PCC.0000000000001058
PMCID: PMC5380529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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