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Article

Multi-ancestry genome-wide association study in all of Us for primary open-angle glaucoma.

Scientific reports - 17 Mar 2026

Tavakoli Kiana, Huang Bonnie B, Mirmira Tara, Ma Nichole, Weinreb Robert N, Baxter Sally L

Abstract excerpt

This study aims to identify new genetic loci associated with primary open-angle glaucoma (POAG) and explore shared genetic risk factors across African, European, and Admixed American/Latino populations. Genome-wide Association Study (GWAS) utilizing data from the All of Us Research Program. The study included 374,254 participants, with 4,305 individuals diagnosed with POAG and 369,949 controls. Participants were...

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Source

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Identifiers

PMID: 41844886
DOI: 10.1038/s41598-026-43993-9
PMCID: PMC13129092

Genes

MOXD1
RYK
TUT4
FAM135B
GATA5
MAF
SLC16A7
TMCO1
TSPAN17
UBAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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