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Article

Macrophage migration inhibitory factor triggers vascular smooth muscle cell dedifferentiation by a p68-serum response factor axis.

Cardiovascular research - 1 Apr 2017

Fan Ye, Zhang Jing, Chen Cai-Yu, Xiao Ying-Bin, Asico Laureano D, Jose Pedro A, Xu Jian-Cheng, Qian Gui-Sheng, Zeng Chun-Yu

Abstract excerpt

AIMS: Macrophage migration inhibitory factor (MIF) is an important proinflammatory mediator linked to arterial diseases. Although its inflammatory property such as macrophage recruitment is known for contributing to vascular pathogenesis, the direct effects of MIF on homeostasis and biological function of vascular smooth muscle cell (VSMC) that are crucial for development of arterial abnormalities, are poorly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28165114
DOI: 10.1093/cvr/cvx025

Genes

MIF
SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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