Article
Macrophage Migration Inhibitory Factor (MIF) Axis Drives Intracranial Aneurysms Macrophage M1 Polarization: Insights from Single-Cell and Bulk RNA Sequencing
2024-04-29
Abstract excerpt
<title>Abstract</title> <p><bold>Background: </bold>Intracranial aneurysms (IAs) develop and progress through pathological processes, including inflammation and abnormal changes in the vascular structure. The cytokine Macrophage Migration Inhibitory Factor (MIF) is implicated in the pathology of vascular diseases. However, the role of MIF in IAs remains to be elucidated. <bold>Methods: </bold>This study utilized...
Topics
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- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Atherosclerosis and Cardiovascular Diseases
- Immune cells in cancer
- Intracranial Aneurysms: Treatment and Complications
- Moyamoya disease diagnosis and treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 3d2cb3e8-095a-5c2a-b438-c385e7169323
- DOI
- 10.21203/rs.3.rs-4268376/v1
