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Detection the Frequency and Characteristics of FLT3 Internal Tandem Duplication Mutations by Capillary Electrophoresis Assay and Next-Generation Sequencing in.

Clinical laboratory - 1 Oct 2016

Ma Liang, Cao Yongyue, Jiang Yongwei, Cong Xiao, Lu Shuang, Shen Jun, Liu Qian, Han Chengwu, Zhan Yuliang, Cao Yongtong

Abstract excerpt

BACKGROUND: FLT3-internal tandem duplication mutations (ITDs) are found in approximately 30% of patients with acute myeloid leukemia (AML) and are markers of poor prognosis. However, the characteristics of FLT3/ ITDs in Chinese AML patients have rarely been reported. The aim of this study was to analyze the frequency and characteristics of FLT3/ITDs in Chinese AML patients. METHODS: In the selected 152 cases of...

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Source

Identifiers

PMID: 28164543
DOI: 10.7754/Clin.Lab.2016.160326

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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