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Article

FMS-like tyrosine kinase 3 internal tandem duplication and the patterns of its gene sequence in 207 Chinese patients with de novo acute myeloid leukemia.

Archives of pathology & laboratory medicine - 1 Jan 2012

Zhong Ling, Jia Yong Qian, Meng Wen Tong, Ni Xun

Abstract excerpt

CONTEXT: Constitutive activation of the FMS-like tyrosine kinase 3 (FLT3) receptor tyrosine kinase by internal tandem duplication (ITD) has been researched in patients with de novo acute myeloid leukemia (AML). OBJECTIVE: To study the patterns of FLT3-ITD in Chinese patients with AML. DESIGN: A total of 207 patients with de novo AML were enrolled in the study. Genomic DNA was extracted from peripheral blood and...

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Identifiers

PMID: 22208491
DOI: 10.5858/arpa.2010-0700-OA

Genes

FLT3

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