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Article

Characterisation and Clinical Significance of FLT3-ITD and non-ITD in Acute Myeloid Leukaemia Patients in Kelantan, Northeast Peninsular Malaysia.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Yunus Noraini Mat, Johan Muhammad Farid, Ali Nagi Al-Jamal Hamid, Husin Azlan, Hussein Abdul Rahim, Hassan Rosline

Abstract excerpt

BACKGROUND: Mutations of the FMS-like tyrosine kinase-3 (FLT3) receptor gene may promote proliferation via activation of multiple signaling pathways. FLT3-internal tandem duplication (FLT3-ITD) is the most common gene alteration found in patients diagnosed with acute myeloid leukaemia (AML) and has been associated with poor prognosis. MATERIALS AND METHODS: We performed mutational analysis of exons 14-15 and 20...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26163606
DOI: 10.7314/apjcp.2015.16.12.4869

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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