Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FLT3 and NPM1 mutations in Chinese patients with acute myeloid leukemia and normal cytogenetics.

Journal of Zhejiang University. Science. B - 1 Oct 2010

Wang Lei, Xu Wei-lai, Meng Hai-tao, Qian Wen-bin, Mai Wen-yuan, Tong Hong-yan, Mao Li-ping, Tong Yin, Qian Jie-jing, Lou Yin-jun, Chen Zhi-mei, Wang Yun-gui, Jin Jie

Abstract excerpt

Mutations of fms-like tyrosine kinase 3 (FLT3) and nucleophosmin (NPM1) exon 12 genes are the most common abnormalities in adult acute myeloid leukemia (AML) with normal cytogenetics. To assess the prognostic impact of the two gene mutations in Chinese AML patients, we used multiplex polymerase c...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD34
Share to Antigens, CD7
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytogenetics

Share to fms-Like Tyrosine Kinase 3

Share to Leukemia, Myeloid, Acute

Share to Nuclear Proteins

Share to Nucleophosmin

Source

Open in PubMed Open full text

Identifiers

PMID: 20872983
DOI: 10.1631/jzus.B1000052
PMCID: PMC2950237

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20872983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FLT3 and NPM1 mutations in Chinese patients with acute myeloid leukemia and normal cytogenetics.PMID 20872983Read ↗

FMS-Like Tyrosine Kinase 3 (FLT3) and Nucleophosmin 1 (NPM1) in Iranian Adult Acute Myeloid Leukemia Patients with Normal Karyotypes: Mutation Status and Clinical and Laboratory Characteristics.Semantic proximity Read ↗

[A study of NPM1 and FLT3 gene mutations in acute myeloid leukemia].Semantic proximity Read ↗

Prognostic implications of NPM1 mutations and FLT3 internal tandem duplications in Egyptian patients with cytogenetically normal acute myeloid leukemia.Semantic proximity Read ↗

Analysis of NPM1 gene mutations in Chinese adults with acute myeloid leukemia.Semantic proximity Read ↗

[C-kit, NPM1 and FLT3 gene mutation patterns and their prognostic significance in 656 Chinese patients with acute myeloid leukemia].Semantic proximity Read ↗

Nucleophosmin mutations in Chinese adults with acute myelogenous leukemia.Semantic proximity Read ↗

Mutation profile and associated clinical features in Chinese patients with cytogenetically normal acute myeloid leukemia.Semantic proximity Read ↗

NPM1 and FLT3 mutations in acute myeloid leukemia with normal karyotype: Indian perspective.Semantic proximity Read ↗

Detection of nucleophosmin and FMS-like tyrosine kinase-3 gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

NPM1, FLT3-ITD, CEBPA, and c-kit mutations in 312 Chinese patients with de novo acute myeloid leukemia.Semantic proximity Read ↗

FLT3 and NPM1 gene mutations in childhood acute myeloblastic leukemia.Semantic proximity Read ↗

[Detection of NPM1, FLT3 and C-KIT mutations in acute myeloid leukemia and their prognostic analysis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.