Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto's disease.

International journal of immunogenetics - 1 Apr 2017

Arakawa Y, Watanabe M, Takemura K, Inoue N, Hidaka Y, Iwatani Y

Abstract excerpt

To clarify the association between the genetic producibility of IL-15, a pro-inflammatory cytokine, and the pathogenesis of autoimmune thyroid diseases (AITDs), we genotyped +96522 A>T and +82889 A>G polymorphisms in the IL15 gene using 127 patients with Hashimoto's disease (HD), including 55 patients with severe HD and 48 patients with mild HD; 130 patients with Graves' disease (GD), including 52 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to CD4-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Graves Disease

Share to Hashimoto Disease

Share to Interleukin-15

Share to Polymorphism, Single Nucleotide

Share to Th17 Cells

Source

Identifiers

PMID: 28164472
DOI: 10.1111/iji.12305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The IL15 +96522 A>T functional polymorphism is related to the differentiation of Th17 cells and the severity of Hashimoto's disease.PMID 28164472Read ↗

Association of functional polymorphisms in promoter regions of IL5, IL6 and IL13 genes with development and prognosis of autoimmune thyroid diseases.Semantic proximity Read ↗

Association of interleukin-16 polymorphisms with graves' disease in a Taiwanese population.Semantic proximity Read ↗

Functional polymorphisms affecting Th1 differentiation are associated with the severity of autoimmune thyroid diseases.Semantic proximity Read ↗

Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene.Semantic proximity Read ↗

The −590CC Genotype in the IL4 Gene as a Strong Predictive Factor for the Development of Hypothyroidism in Hashimoto DiseaseSemantic proximity Read ↗

IL-10 -592A/C polymorphism is associated with severity of Hashimoto's disease.Semantic proximity Read ↗

Association of the interleukin (IL)-16 gene polymorphisms with Graves' disease.Semantic proximity Read ↗

Involvement of functional polymorphisms in the TNFA gene in the pathogenesis of autoimmune thyroid diseases and production of anti-thyrotropin receptor antibody.Semantic proximity Read ↗

TNFSF15 Polymorphisms are Associated with Graves' Disease and Graves' Ophthalmopathy in a Han Chinese Population.Semantic proximity Read ↗

Multilocus haplotype analyses reveal association between 5 novel IL-15 polymorphisms and asthma.Semantic proximity Read ↗

Correlations between growth differentiation factor 15 (GDF-15) serum levels and gene polymorphism with type 2 diabetes mellitusSemantic proximity Read ↗

Association of the -31C/T functional polymorphism in the interleukin-1beta gene with the intractability of Graves' disease and the proportion of T helper type 17 cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.