Article
Multilocus haplotype analyses reveal association between 5 novel IL-15 polymorphisms and asthma.
The Journal of allergy and clinical immunology - 1 May 2004
Kurz Thorsten, Strauch Konstantin, Dietrich Henriette, Braun Sandra, Hierl Steffen, Jerkic Silvija-Pera, Wienker Thomas F, Deichmann Klaus A, Heinzmann Andrea
Abstract excerpt
BACKGROUND: IL-15 is a T(H)1-related cytokine that is involved in the inflammatory response in various infectious and autoimmune diseases. IL-15 has recently been shown to be upregulated in T-cell-mediated inflammatory disorders. The observations suggest a potential role for this cytokine in a variety of pathologic conditions, including T(H)1-mediated and T(H)2-mediated inflammatory diseases. OBJECTIVE: In this...
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