Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma.

Cancer letters - 28 Apr 2017

Malfettone Andrea, Soukupova Jitka, Bertran Esther, Crosas-Molist Eva, Lastra Raquel, Fernando Joan, Koudelkova Petra, Rani Bhavna, Fabra Ángels, Serrano Teresa, Ramos Emilio, Mikulits Wolfgang, Giannelli Gianluigi, Fabregat Isabel

Abstract excerpt

As part of its potential pro-tumorigenic actions, Transforming Growth Factor-(TGF)-β induces epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC) cells. Whether EMT induces changes in tumor cell plasticity has not been fully explored yet. Here, we analyze the effects of TGF-β on the EMT and stem-related properties of HCC cells and the potential correlation among those processes. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Plasticity
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyaluronan Receptors

Share to Mesenchymal Stem Cells

Share to Neoplastic Stem Cells

Share to Receptor, Transforming Growth Factor-beta Type I

Share to Receptors, Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 28161507
DOI: 10.1016/j.canlet.2017.01.037

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma.PMID 28161507Read ↗

Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?Semantic proximity Read ↗

Stromal signals dominate gene expression signature scores that aim to describe cancer-intrinsic stemness or mesenchymality characteristicsSemantic proximity Read ↗

TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancerSemantic proximity Read ↗

Stemness and chemoresistance are imparted to the OC cells through TGFβ1 driven EMTSemantic proximity Read ↗

Epithelial–mesenchymal transition and cancer stemness: the Twist1–Bmi1 connectionSemantic proximity Read ↗

Harnessing Carcinoma Cell Plasticity Mediated by TGF-β SignalingSemantic proximity Read ↗

Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune ResponseSemantic proximity Read ↗

Epithelial–mesenchymal transition (EMT): A biological process in the development, stem cell differentiation, and tumorigenesisSemantic proximity Read ↗

Quantifying Cancer Epithelial-Mesenchymal Plasticity and its Association with Stemness and Immune ResponseSemantic proximity Read ↗

Stromal Signals Dominate Gene Expression Signature Scores That Aim to Describe Cancer Cell–intrinsic Stemness or Mesenchymality CharacteristicsSemantic proximity Read ↗

A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transitionSemantic proximity Read ↗

Conversion to stem-cell state in response to microenvironmental cues is regulated by balance between epithelial and mesenchymal features in lung cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.