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Article

TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer

30 Jun 2020

Abstract excerpt

Transforming growth factor-β (TGF-β) promotes tumor invasion and metastasis by inducing epithelial-mesenchymal transition (EMT). EMT is often related with acquisition of stemness characteristics. The objective of this study was to determine whether EMT and stemness characteristics induced by TGF-β might be associated with epigenetic regulation in lung cancer. A human normal lung epithelial cell line and four lung...

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PMID: 32606331
DOI: 10.1038/s41598-020-67325-7

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