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Article

Plasmid-Mediated OqxAB Is an Important Mechanism for Nitrofurantoin Resistance in Escherichia coli.

Antimicrobial agents and chemotherapy - 1 Jan 2016

Ho Pak-Leung, Ng Ka-Ying, Lo Wai-U, Law Pierra Y, Lai Eileen Ling-Yi, Wang Ya, Chow Kin-Hung

Abstract excerpt

Increasing consumption of nitrofurantoin (NIT) for treatment of acute uncomplicated urinary tract infections (UTI) highlights the need to monitor emerging NIT resistance mechanisms. This study investigated the molecular epidemiology of the multidrug-resistant efflux gene oqxAB and its contribution to nitrofurantoin resistance by using Escherichia coli isolates originating from patients with UTI (n = 205;...

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Identifiers

PMID: 26552976
DOI: 10.1128/AAC.02156-15
PMCID: PMC4704224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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