Plasmid-mediated quinolone resistance determinants oqxAB and aac(6')-Ib-cr and extended-spectrum  -lactamase gene blaCTX-M-24 co-located on the same plasmid in one Escherichia coli strain from China

Abstract excerpt

Sir, With the common use of fluoroquinolones in both human and animal diseases, fluoroquinolone resistance in veterinary clinics has become an important public health problem since the discovery of horizontally transmissible elements, such as plasmids. To date, a number of plasmid-mediated quinolone resistance (PMQR) determinants have been described: the qnr genes (A, B, S, C and D); the aac(6′)-Ib-cr gene; and...

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