Article
The Future of Janus Kinase Inhibitors in Inflammatory Bowel Disease.
Journal of Crohn's & colitis - 1 Jul 2017
De Vries L C S, Wildenberg M E, De Jonge W J, D'Haens G R
Abstract excerpt
Inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, are disabling conditions characterised by chronic, relapsing inflammation of the gastrointestinal tract. Current treatments are not universally effective or, in the case of therapeutic antibodies, are hampered by immune responses. Janus kinase inhibitors are orally delivered small molecules that target cytokine signalling by preventing...
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