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Article

Immunomodulators in inflammatory bowel disease: an emerging role for biologic agents.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy - 1 Dec 2013

Kemp Roslyn, Dunn Elliott, Schultz Michael

Abstract excerpt

Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel diseases (IBD), are the result of an aberrant immune response to ubiquitous antigens in a genetically susceptible host. In the past, treatment has focused on immunosuppression with the aim of achieving symptom-free remission. Over the last two decades, with a better understanding of the underlying pathomechanisms and an...

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PMID: 23749336
DOI: 10.1007/s40259-013-0045-2

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TNF

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