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JAK selectivity: more precision less troubles

10 Jun 2020

Abstract excerpt

INTRODUCTION: Janus kinases inhibitors (JAKi) are new small molecules recently introduced in the armamentarium of treatments for Inflammatory Bowel Disease (IBD). Janus Kinases (JAK) are tyrosine kinases that act by linkage with different intracellular receptors, regulating cytokines gene transcription implicated in the inflammatory burden seen in IBD patients. AREAS COVERED: A comprehensive literature search was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32520647
DOI: 10.1080/17474124.2020.1780120

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