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Article

The Epigenetic Landscape of Acute Myeloid Leukemia

1 Jan 2014

Abstract excerpt

Acute myeloid leukemia (AML) is a genetically heterogeneous disease. Certain cytogenetic and molecular genetic mutations are recognized to have an impact on prognosis, leading to their inclusion in some prognostic stratification systems. Recently, the advent of high-throughput whole genome or exome sequencing has led to the identification of several novel recurrent mutations in AML, a number of which have been...

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PMID: 24778653
DOI: 10.1155/2014/103175

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