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Article

Stochastic switching as a survival strategy in fluctuating environments.

Nature genetics - 1 Apr 2008

Acar Murat, Mettetal Jerome T, van Oudenaarden Alexander

Abstract excerpt

A classic problem in population and evolutionary biology is to understand how a population optimizes its fitness in fluctuating environments. A population might enhance its fitness by allowing individual cells to stochastically transition among multiple phenotypes, thus ensuring that some cells are always prepared for an unforeseen environmental fluctuation. Here we experimentally explore how switching affects...

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PMID: 18362885
DOI: 10.1038/ng.110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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