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Article

Enhancement of cellular memory by reducing stochastic transitions.

Nature - 12 May 2005

Acar Murat, Becskei Attila, van Oudenaarden Alexander

Abstract excerpt

On induction of cell differentiation, distinct cell phenotypes are encoded by complex genetic networks. These networks can prevent the reversion of established phenotypes even in the presence of significant fluctuations. Here we explore the key parameters that determine the stability of cellular memory by using the yeast galactose-signalling network as a model system. This network contains multiple nested...

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PMID: 15889097
DOI: 10.1038/nature03524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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