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Article

Variation in the modality of a yeast signaling pathway is mediated by a single regulator.

eLife - 9 Aug 2021

Palme Julius, Wang Jue, Springer Michael

Abstract excerpt

Bimodal gene expression by genetically identical cells is a pervasive feature of signaling networks and has been suggested to allow organisms to hedge their 'bets' in uncertain conditions. In the galactose-utilization (GAL) pathway of Saccharomyces cerevisiae, gene induction is unimodal or bimodal depending on natural genetic variation and pre-induction conditions. Here, we find that this variation in modality...

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Share to Galactose
Share to Gene Expression Regulation, Fungal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34369878
DOI: 10.7554/eLife.69974
PMCID: PMC8373380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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