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Article

Endosialin Promotes Atherosclerosis Through Phenotypic Remodeling of Vascular Smooth Muscle Cells.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2017

Hasanov Zulfiyya, Ruckdeschel Tina, König Courtney, Mogler Carolin, Kapel Stephanie S, Korn Claudia, Spegg Carleen, Eichwald Viktoria, Wieland Matthias, Appak Sila, Augustin Hellmut G

Abstract excerpt

OBJECTIVE: Vascular smooth muscle cells (VSMC) play a key role in the pathogenesis of atherosclerosis, the globally leading cause of death. The transmembrane orphan receptor endosialin (CD248) has been characterized as an activation marker of cells of the mesenchymal lineage including tumor-associated pericytes, stromal myofibroblasts, and activated VSMC. We, therefore, hypothesized that VSMC-expressed endosialin...

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Identifiers

PMID: 28126825
DOI: 10.1161/ATVBAHA.116.308455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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