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Article

Endothelial-mesenchymal transition in atherosclerosis.

Cardiovascular research - 15 Mar 2018

Souilhol Celine, Harmsen Martin C, Evans Paul C, Krenning Guido

Abstract excerpt

Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal cells, lipids, and extracellular matrix. The source of mesenchymal cells in the atherosclerotic plaques has been under scrutiny for years. Current endothelial-lineage tracing studies indicate that the endothelium is a source for...

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Identifiers

PMID: 29309526
DOI: 10.1093/cvr/cvx253

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