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Article

Neutral vs. non-neutral genetic footprints of Plasmodium falciparum multiclonal infections.

PLoS computational biology - 1 Jan 2023

Labbé Frédéric, He Qixin, Zhan Qi, Tiedje Kathryn E, Argyropoulos Dionne C, Tan Mun Hua, Ghansah Anita, Day Karen P, Pascual Mercedes

Abstract excerpt

At a time when effective tools for monitoring malaria control and eradication efforts are crucial, the increasing availability of molecular data motivates their application to epidemiology. The multiplicity of infection (MOI), defined as the number of genetically distinct parasite strains co-infecting a host, is one key epidemiological parameter for evaluating malaria interventions. Estimating MOI remains a...

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PMID: 36595546
DOI: 10.1371/journal.pcbi.1010816
PMCID: PMC9838855

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