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Article

Accuracy of Plasmodium falciparum genetic data for estimating parasite prevalence and malaria incidence in Uganda.

Malaria journal - 21 Feb 2026

Kiyaga Shahiid, Mbabazi Monica, Katairo Thomas, Kabbale Kisakye Diana, Asua Victor, Nsengimaana Bienvenu, Wiringilimaana Innocent, Semakuba Francis Ddumba, Mwubaha Caroline, Nakasaanya Jackie, Watyekele Eric, Ayitewala Alisen, Tukwasibwe Stephen, Mulondo Jerry, Nsobya Samuel Lubwama, Agaba Bosco, Maiteki-Sebuguzi Catherine, Kamya Moses Robert, Kateete David Patrick, Nabende Joyce Nakatumba, Jjingo Daudi, Mboowa Gerald, Batte Charles, Ssewanyana Isaac, Aranda-Díaz Andrés, Dorsey Grant, Rosenthal Philip J, Conrad Melissa, Greenhouse Bryan, Briggs Jessica

Abstract excerpt

BACKGROUND: Genetic metrics derived from Plasmodium falciparum infections offer a potential complement to conventional malaria surveillance by utilizing features of parasite diversity and relatedness to estimate transmission intensity. However, the performance of genetic metrics to predict epidemiologic metrics across a wide range of transmission settings remains understudied. METHODS: Dried blood spots from 3563...

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Identifiers

PMID: 41723456
DOI: 10.1186/s12936-026-05836-w
PMCID: PMC13032663

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