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Article

Structural Consequences of Calmodulin EF Hand Mutations.

Biochemistry - 21 Feb 2017

Piazza Michael, Taiakina Valentina, Dieckmann Thorsten, Guillemette J Guy

Abstract excerpt

Calmodulin (CaM) is a cytosolic Ca2+-binding protein that serves as a control element for many enzymes. It consists of two globular domains, each containing two EF hand pairs capable of binding Ca2+, joined by a flexible central linker region. CaM is able to bind and activate its target proteins in the Ca2+-replete and Ca2+-deplete forms. To study the Ca2+-dependent/independent properties of binding and...

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Identifiers

PMID: 28121131
DOI: 10.1021/acs.biochem.6b01296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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