Article
Calmodulin Mutations in Human Disease.
Channels (Austin, Tex.) - 1 Dec 2023
Hussey John W, Limpitikul Worawan B, Dick Ivy E
Abstract excerpt
Calcium ions (Ca2+) are the basis of a unique and potent array of cellular responses. Calmodulin (CaM) is a small but vital protein that is able to rapidly transmit information about changes in Ca2+ concentrations to its regulatory targets. CaM plays a critical role in cellular Ca2+ signaling, and interacts with a myriad of target proteins. Ca2+-dependent modulation by CaM is a major component of a diverse array...
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