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Article

Phenotypic and genotypic correlates of daptomycin-resistant methicillin-susceptible Staphylococcus aureus clinical isolates.

Journal of microbiology (Seoul, Korea) - 1 Feb 2017

Kang Kyoung-Mi, Mishra Nagendra N, Park Kun Taek, Lee Gi-Yong, Park Yong Ho, Bayer Arnold S, Yang Soo-Jin

Abstract excerpt

Daptomycin (DAP) has potent activity in vitro and in vivo against both methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) strains. DAP-resistance (DAP-R) in S. aureus has been mainly observed in MRSA strains, and has been linked to single nucleotide polymorphisms (SNPs) within the mprF gene leading to altered cell membrane (CM) phospholipid (PL) profiles, enhanced...

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Identifiers

PMID: 28120188
DOI: 10.1007/s12275-017-6509-1
PMCID: PMC6218394

Genes

DAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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