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Article

Co-transmission of Related Malaria Parasite Lineages Shapes Within-Host Parasite Diversity.

Cell host & microbe - 8 Jan 2020

Nkhoma Standwell C, Trevino Simon G, Gorena Karla M, Nair Shalini, Khoswe Stanley, Jett Catherine, Garcia Roy, Daniel Benjamin, Dia Aliou, Terlouw Dianne J, Ward Stephen A, Anderson Timothy J C, Cheeseman Ian H

Abstract excerpt

In high-transmission regions, we expect parasite lineages within complex malaria infections to be unrelated due to parasite inoculations from different mosquitoes. This project was designed to test this prediction. We generated 485 single-cell genome sequences from fifteen P. falciparum malaria patients from Chikhwawa, Malawi-an area of intense transmission. Patients harbored up to seventeen unique parasite...

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Identifiers

PMID: 31901523
DOI: 10.1016/j.chom.2019.12.001
PMCID: PMC7159252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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