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Plasmodium falciparum genomic surveillance reveals spatial and temporal trends, association of genetic and physical distance, and household clustering.

Scientific reports - 18 Jan 2022

Sy Mouhamad, Deme Awa B, Warren Joshua L, Early Angela, Schaffner Stephen, Daniels Rachel F, Dieye Baba, Ndiaye Ibrahima Mbaye, Diedhiou Younous, Mbaye Amadou Moctar, Volkman Sarah K, Hartl Daniel L, Wirth Dyann F, Ndiaye Daouda, Bei Amy K

Abstract excerpt

Molecular epidemiology using genomic data can help identify relationships between malaria parasite population structure, malaria transmission intensity, and ultimately help generate actionable data to assess the effectiveness of malaria control strategies. Genomic data, coupled with geographic information systems data, can further identify clusters or hotspots of malaria transmission, parasite genetic and spatial...

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PMID: 35042879
DOI: 10.1038/s41598-021-04572-2
PMCID: PMC8766587

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