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Article

Dramatic Changes in Malaria Population Genetic Complexity in Dielmo and Ndiop, Senegal, Revealed Using Genomic Surveillance.

The Journal of infectious diseases - 30 Jan 2018

Bei Amy K, Niang Makhtar, Deme Awa B, Daniels Rachel F, Sarr Fatoumata D, Sokhna Cheikh, Talla Cheikh, Faye Joseph, Diagne Nafissatou, Doucoure Souleymane, Mboup Souleymane, Wirth Dyann F, Tall Adama, Ndiaye Daouda, Hartl Daniel L, Volkman Sarah K, Toure-Balde Aissatou

Abstract excerpt

Dramatic changes in transmission intensity can impact Plasmodium population diversity. Using samples from 2 distant time-points in the Dielmo/Ndiop longitudinal cohorts from Senegal, we applied a molecular barcode tool to detect changes in parasite genotypes and complexity of infection that corresponded to changes in transmission intensity. We observed a striking statistically significant difference in genetic...

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Identifiers

PMID: 29325146
DOI: 10.1093/infdis/jix580
PMCID: PMC6279132

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Source receipt: pubmed, retrieved 7 Sept 2026.

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