Article
Genetic surveillance detects both clonal and epidemic transmission of malaria following enhanced intervention in Senegal.
PloS one - 1 Jan 2013
Daniels Rachel, Chang Hsiao-Han, Séne Papa Diogoye, Park Danny C, Neafsey Daniel E, Schaffner Stephen F, Hamilton Elizabeth J, Lukens Amanda K, Van Tyne Daria, Mboup Souleymane, Sabeti Pardis C, Ndiaye Daouda, Wirth Dyann F, Hartl Daniel L, Volkman Sarah K
Abstract excerpt
Using parasite genotyping tools, we screened patients with mild uncomplicated malaria seeking treatment at a clinic in Thiès, Senegal, from 2006 to 2011. We identified a growing frequency of infections caused by genetically identical parasite strains, coincident with increased deployment of malaria control interventions and decreased malaria deaths. Parasite genotypes in some cases persisted clonally across dry...
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