Article
Modeling malaria genomics reveals transmission decline and rebound in Senegal.
Proceedings of the National Academy of Sciences of the United States of America - 2 Jun 2015
Daniels Rachel F, Schaffner Stephen F, Wenger Edward A, Proctor Joshua L, Chang Hsiao-Han, Wong Wesley, Baro Nicholas, Ndiaye Daouda, Fall Fatou Ba, Ndiop Medoune, Ba Mady, Milner Danny A, Taylor Terrie E, Neafsey Daniel E, Volkman Sarah K, Eckhoff Philip A, Hartl Daniel L, Wirth Dyann F
Abstract excerpt
To study the effects of malaria-control interventions on parasite population genomics, we examined a set of 1,007 samples of the malaria parasite Plasmodium falciparum collected in Thiès, Senegal between 2006 and 2013. The parasite samples were genotyped using a molecular barcode of 24 SNPs. About 35% of the samples grouped into subsets with identical barcodes, varying in size by year and sometimes persisting...
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