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Article

Alcohol use disorder and GABAB receptor gene polymorphisms in an Italian sample: haplotype frequencies, linkage disequilibrium and association studies.

Annals of human biology - 1 Jun 2017

Caputo Fabio, Ciminelli Bianca Maria, Jodice Carla, Blasi Paola, Vignoli Teo, Cibin Mauro, Zoli Giorgio, Malaspina Patrizia

Abstract excerpt

BACKGROUND: Alcohol use disorder (AUD) is a complex trait with genetic and environmental influences. Several gene variants have been associated with the risk for AUD, including genes encoding the sub-units of the γ-aminobutyric acid (GABA) receptors. AIM: This study evaluated whether specific single nucleotide polymorphisms (SNPs) in genes encoding GABAB receptor sub-units can be considered as candidates for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28118741
DOI: 10.1080/03014460.2017.1287307

Genes

GABBR2
GABBR1

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