Article
Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR).
PloS one - 1 Jan 2017
Giannios Ioannis, Chatzantonaki Eleftheria, Georgatos Spyros
Abstract excerpt
The lamin B receptor (LBR) is a multi-spanning membrane protein of the inner nuclear membrane that is often employed as a "reporter" of nuclear envelope dynamics. We show here that the diffusional mobility of full-length LBR exhibits significant regional variation along the nuclear envelope, consistent with the existence of discrete LBR microdomains and the occurrence of multiple, asymmetrically-spaced...
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